Prostate Cancer Research Today is a free monthly online journal that collates and summarizes the latest research about Prostate Cancer, including details on symptoms, genetics, screening, treatment, information.

Interfering with cell-survival signalling as a treatment strategy for prostate cancer.

Corcoran NM, Costello AJ, Hovens CM

Department of Urology, University of Melbourne, Royal Melbourne Hospital, Parkville, Victoria, Australia. niall.corcoran@mh.org.au

Authors from Australia describe how interfering with cell survival is increasingly being chosen as a method of developing a treatment strategy for hormone-resistant prostate cancer. The authors show how several developmental drug candidates have preclinical and clinical activity against cell survival proteins, and that these might be worth considering as possible clinical entities in this condition. The commonly stated argument that laparoscopy has advanced the cause of donor nephrectomy in renal transplantation is examined by authors from the UK. They present a review of the published reports and show that the evidence base is poor for drawing a conclusion as to whether laparoscopic or open nephrectomy is best.

Published 11 May 2006 in BJU Int, 97(6): 1149-53.
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